Serum 25-Hydroxyvitamin-D Level in Full-term Neonates with Indirect Hyperbilirubinemia at a Level Requiring Phototherapy

Background: Low antioxidant system may contribute to the severity of neonatal hyperbilirubinemia. Aim work: This study was performed clarify relationship between serum   25-hydroxyvitamin-D (25[OH] D) and hyperbilirubinemia in full-term neonates. Methods: This is a cross sectional case control with aim determining whether there an association serum indirect bilirubin vitamin D levels newborns jaundice at level necessitating phototherapy. The carried on 60 full term admitted Neonatal Intensive Care Unit Minia University Hospital, from April 2017 December 2017. They were classified into 2 groups, Group I: (cases): Newborns postnatal ages 3-10 days gestational 37-40 weeks, above pre-set threshold for phototherapy as recommended by American Academy Pediatrics (AAP). II :( controls) 30 matched apparently normal healthy enrolled group. included mothers All laboratory investigations done clinical pathology department, hospital. Results: Serum Vitamin significantly lower patients than controls (p < 0.01). There strong negative correlation total cases In addition, we observed that highly statistically significant positive neonates their maternal present. Conclusions: Indirect associated decreased